Molecular pharmacology of gonadotropins.
Endocrine
; 26(3): 291-6, 2005 Apr.
Article
em En
| MEDLINE
| ID: mdl-16034184
ABSTRACT
Gonadotropins have been studied in biological systems for decades and many of their properties are well defined. These include pharmacological properties such as affinity, stability, and pharmacokinetics also used to characterize drugs. Technologies applied to research on gonadotropins have led to the creation of hormone analogs with alterations to one or more of these proper-ties. Some of these analogs have potential therapeutic applications. A challenge to realizing this potential is the accurate prediction of how these compounds will perform in humans. This could be facilitated by advances in biological models and the understanding of specific effects of the hormones on their receptors.
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Base de dados:
MEDLINE
Assunto principal:
Hormônio Luteinizante
/
Desenho de Fármacos
/
Hormônio Foliculoestimulante
Idioma:
En
Ano de publicação:
2005
Tipo de documento:
Article