Neutrophils and eosinophils: clinical implications of their appearance, presence and disappearance in asthma and COPD.
Curr Drug Targets Inflamm Allergy
; 4(4): 415-23, 2005 Aug.
Article
em En
| MEDLINE
| ID: mdl-16101518
ABSTRACT
Asthma and chronic obstructive pulmonary disease (COPD) are common chronic disorders. Traditionally, asthma has been associated with an eosinophilic inflammation and COPD with neutrophilic inflammation. In this review we will highlight the maturation, recruitment, activation, action and apoptosis of these cells. In addition we will focus on the evidence for their presence in disease and suggest potential new therapeutic interventions.
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Base de dados:
MEDLINE
Assunto principal:
Asma
/
Doença Pulmonar Obstrutiva Crônica
/
Eosinófilos
/
Neutrófilos
Idioma:
En
Ano de publicação:
2005
Tipo de documento:
Article