Determination of promethazine hydrochloride and its preparations by highly accurate nephelometric titration.

Zhang, Qi; Zhan, Xiancheng; Li, Chengrong; Lin, Tao; Li, Linli; Yin, Xiaodong; He, Ning; Shi, Yan

Zhang, Qi; Zhan, Xiancheng; Li, Chengrong; Lin, Tao; Li, Linli; Yin, Xiaodong; He, Ning; Shi, Yan.

Afiliação

Zhang Q; West China School of Pharmacy, Sichuan University, No. 17, Section 3, Ren-Min-Nan-Lu Rd., Chengdu, Sichuan 610041, PR China.

Int J Pharm ; 302(1-2): 10-7, 2005 Sep 30.

Article em En | MEDLINE | ID: mdl-16122890

ABSTRACT

ABSTRACT

A highly accurate nephelometric titration for the determination of promethazine hydrochloride and its preparations was presented. The titration operating conditions were studied and the solubility product constant of promethazine tetraphenylboron precipitation was determined. The result of the titration is comparable to those of control experiments. The proposed method has been found to be accurate, precise, specific and linear.

Assuntos

Nefelometria e Turbidimetria/métodos; Preparações Farmacêuticas/análise; Prometazina/análise; Titulometria/métodos; Nefelometria e Turbidimetria/instrumentação; Reprodutibilidade dos Testes; Comprimidos; Tecnologia Farmacêutica/métodos; Titulometria/tendências

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Base de dados: MEDLINE Assunto principal: Prometazina / Preparações Farmacêuticas / Titulometria / Nefelometria e Turbidimetria Idioma: En Ano de publicação: 2005 Tipo de documento: Article

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