Association between atopy and recurrent vaginal candidiasis.
Clin Exp Immunol
; 142(1): 167-71, 2005 Oct.
Article
em En
| MEDLINE
| ID: mdl-16178872
ABSTRACT
To determine whether there is an association between atopy and recurrent vaginal candidiasis (RVC) and to evaluate the type-2 immune response in patients with RVC. Evaluation of immediate hypersensitivity skin tests to aeroallergens, measurement of total IgE and Candida albicans specific IgE and levels of IL-5 in 44 women with RVC and 26 with sporadic vaginal candidiasis (SVC). Statistical analyses were performed by Mann-Whitney test and chi(2) test with Yates correction. History of atopy (68%) and positive skin test (42%) were higher (P < 0.05) in RVC than in patients with SVC. No significant difference was found in total IgE, C. albicans specific IgE and IL-5 levels. There was a strong association between atopy and RVC, but type-2 immune response to C. albicans antigen was absent or similar in the two groups of patients.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Candidíase Vulvovaginal
/
Hipersensibilidade Imediata
Idioma:
En
Ano de publicação:
2005
Tipo de documento:
Article