Memory interference in multiple sclerosis.
J Int Neuropsychol Soc
; 11(6): 737-46, 2005 Oct.
Article
em En
| MEDLINE
| ID: mdl-16248909
ABSTRACT
To explore verbal memory impairments associated with multiple sclerosis (MS), we compared proactive and retroactive interference effects on the California Verbal Learning Test (CVLT; Delis et al., 1987) in a sample of 83 community-residing individuals with MS and 80 healthy participants. Individuals with MS demonstrated normal accumulation of proactive interference (PI), but attenuated release from PI relative to healthy individuals. Furthermore, accumulation of retroactive interference (RI) at short-delay free recall (SDFR) was intensified for those with MS as compared to healthy participants. Interestingly, accumulation of RI predicted long-term memory (LTM) only for participants with MS. These findings suggest that individuals with MS may experience particular difficulty when required to use semantic properties of information flexibly to facilitate verbal LTM.
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Base de dados:
MEDLINE
Assunto principal:
Memória
/
Transtornos da Memória
/
Esclerose Múltipla
Idioma:
En
Ano de publicação:
2005
Tipo de documento:
Article