Recombinant polymers for cancer gene therapy: a minireview.
J Control Release
; 109(1-3): 108-19, 2005 Dec 05.
Article
em En
| MEDLINE
| ID: mdl-16263190
ABSTRACT
A major challenge for successful cancer gene therapy is the development of safe and effective gene delivery vectors. Gene delivery vectors can be viral or nonviral. Among nonviral vectors various polymeric vectors have shown potential in gene delivery. However, much work needs to be done in order to correlate polymer structure with gene release at the target site and transfection efficiency. This article is a brief introduction into cancer gene therapy, barriers and methods for gene transfer with emphasis on the applications of recombinant polymers for cancer gene therapy.
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Base de dados:
MEDLINE
Assunto principal:
Proteínas Recombinantes
/
Terapia Genética
/
Neoplasias
Idioma:
En
Ano de publicação:
2005
Tipo de documento:
Article