Improved cellular response of osteoblast cells using recombinant human osteopontin protein produced by Escherichia coli.
Biotechnol Lett
; 27(22): 1767-70, 2005 Nov.
Article
em En
| MEDLINE
| ID: mdl-16314968
ABSTRACT
Osteopontin is a major non-collagenous bone matrix protein secreted into the mineralizing extracellular matrix by osteoblasts during bone development. Recombinant human osteopontin (hOPN) that includes the Arg-Gly-Asp (RGD) cell recognition site was expressed in Escherichia coli and the purified osteopontin increased cell adhesion, proliferation and differentiation of osteoblast cells (p<0.05).
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Osteoblastos
/
Osteogênese
/
Sialoglicoproteínas
/
Técnicas de Cultura de Células
/
Engenharia Tecidual
/
Escherichia coli
Idioma:
En
Ano de publicação:
2005
Tipo de documento:
Article