Herpesvirus interference with virus-specific antibodies: bridging antibodies, internalizing antibodies, and hiding from antibodies.
Vet Microbiol
; 113(3-4): 257-63, 2006 Mar 31.
Article
em En
| MEDLINE
| ID: mdl-16326036
ABSTRACT
Herpesviruses have developed different tools to thwart efficient antibody-dependent neutralisation and lysis of virions and elimination of infected cells. This overview will briefly summarize different of these tools, including (i) viral Fc receptors and the resulting process of antibody bridging, (ii) internalization of individual viral proteins and clustered antibody-antigen complexes from the plasma membrane of infected cells, and (iii) directed egress of virus particles to sites of intimate cell-cell contact that are difficult to access for antibodies.
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Base de dados:
MEDLINE
Assunto principal:
Proteínas do Envelope Viral
/
Herpesviridae
/
Anticorpos Antivirais
Idioma:
En
Ano de publicação:
2006
Tipo de documento:
Article