A distributed computation of Interpro Pfam, PROSITE and ProDom for protein annotation.
Genet Mol Res
; 4(3): 590-8, 2005 Sep 30.
Article
em En
| MEDLINE
| ID: mdl-16342044
ABSTRACT
Interpro is a widely used tool for protein annotation in genome sequencing projects, demanding a large amount of computation and representing a huge time-consuming step. We present a strategy to execute programs using databases Pfam, PROSITE and ProDom of Interpro in a distributed environment using a Java-based messaging system. We developed a two-layer scheduling architecture of the distributed infrastructure. Then, we made experiments and analyzed the results. Our distributed system gave much better results than Interpro Pfam, PROSITE and ProDom running in a centralized platform. This approach seems to be appropriate and promising for highly demanding computational tools used for biological applications.
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Base de dados:
MEDLINE
Assunto principal:
Sistemas de Gerenciamento de Base de Dados
/
Projeto Genoma Humano
/
Biologia Computacional
/
Análise de Sequência de Proteína
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Bases de Dados de Proteínas
Idioma:
En
Ano de publicação:
2005
Tipo de documento:
Article