Asthma genetics 2006: the long and winding road to gene discovery.
Genes Immun
; 7(2): 95-100, 2006 Mar.
Article
em En
| MEDLINE
| ID: mdl-16395390
ABSTRACT
Asthma and atopy are complex phenotypes that are influenced by both genetic and environmental factors. A review of nearly 500 papers on disease association studies identified 25 genes that have been associated with an asthma or atopy phenotype in six or more populations. An additional 54 genes have been associated in 2-5 populations. Here, we discuss the methods that have been used to identify susceptibility genes for common diseases and overview the status of asthma genetic research. Finally, current challenges and future directions are discussed.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Asma
/
Predisposição Genética para Doença
Idioma:
En
Ano de publicação:
2006
Tipo de documento:
Article