Prolactin excess: treatment and toxicity.
Pediatr Endocrinol Rev
; 2 Suppl 1: 108-14, 2004 Nov.
Article
em En
| MEDLINE
| ID: mdl-16456489
ABSTRACT
Dopamine agonists provide highly effective therapy for the treatment of hyperprolactinemia. As a result of their efficacy and tolerability, these agents are considered to be the initial therapy of choice in children, adolescents and adults with idiopathic hyperprolactinemia and prolactinomas. The four dopamine agonists, bromocriptine, pergolide, cabergoline and quinagolide, share a similar mechanism of action and side effect profile. Although studies of cabergoline have demonstrated the highest treatment efficacy and tolerability, all four of these agents are safe, effective and tolerable in children and adolescents. When fertility is desired, bromocriptine is generally preferable, but cabergoline is also likely safe; pergolide and quinagolide should not be used in this setting.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias Hipofisárias
/
Hiperprolactinemia
/
Prolactinoma
/
Agonistas de Dopamina
Idioma:
En
Ano de publicação:
2004
Tipo de documento:
Article