[Genome-wide analysis for transcriptional regulation of chondrogenesis-related genes].
Clin Calcium
; 16(2): 360- 67, 2006 Feb.
Article
em Ja
| MEDLINE
| ID: mdl-16465042
ABSTRACT
Transcriptional factor Sox9 plays a central role in development of chondrogenesis with stage specificity and in tissue specificity. Sox9 with a number of transcriptional cofactors is a critical regulator in genes such as COL2, chondorocyte specific gene. We report here our new large scale approaches 1) Whole mount in situ hybridization (WISH), 2) High through-put human cDNA transfection assay. These genome-wide approaches have a possibility of discovery for new transcription factors in chondrogenesis.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Fatores de Transcrição
/
Transcrição Gênica
/
Proteínas de Grupo de Alta Mobilidade
/
Condrogênese
Idioma:
Ja
Ano de publicação:
2006
Tipo de documento:
Article