Can the passive elasticity of muscle be explained directly from the mechanics of individual titin molecules?
J Muscle Res Cell Motil
; 26(6-8): 285-9, 2005.
Article
em En
| MEDLINE
| ID: mdl-16465473
ABSTRACT
Recent progress in understanding the role of titin/connectin in muscle elasticity has been heavily based on results from single molecule mechanical experiments. The shape of force-extension curves from such data is similar to curves from muscle fibres and it has been tempting to assume that muscle elasticity can be extrapolated directly from the single molecule data. In this paper we discuss some of the factors that act on titin in the sarcomere that are likely to preclude such a direct extrapolation.
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Base de dados:
MEDLINE
Assunto principal:
Proteínas Quinases
/
Contração Muscular
/
Proteínas Musculares
Idioma:
En
Ano de publicação:
2005
Tipo de documento:
Article