[Association between high activity of DNA polymerase iota and the development of human uveal melanoma].
Genetika
; 42(1): 98-103, 2006 Jan.
Article
em Ru
| MEDLINE
| ID: mdl-16523672
ABSTRACT
Enzymatic activity of DNA polymerase iota (Pol t) was analyzed in human uveal melanoma cell extracts, using an earlier elaborated approach. The Pol t activity was observed in seven out of eight malignant tumors, while it was absent in the normal uveal tract cells of the same patients. These findings serve as an additional confirmation of the Pol t oncogenic potential.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias Uveais
/
DNA Polimerase Dirigida por DNA
/
Melanoma
Idioma:
Ru
Ano de publicação:
2006
Tipo de documento:
Article