Tumorigenicity of EBV-carrying lymphoblastoid cell lines (LCLs): distinctive grading in SCID mice.
Int J Cancer
; 49(4): 587-91, 1991 Oct 21.
Article
em En
| MEDLINE
| ID: mdl-1655664
ABSTRACT
The in vitro and in vivo growth of lymphoblastoid cell lines (LCLs), Burkitt lymphomas (BLs) and PBL-derived immunoblastomas in SCID mice was studied in parallel. Most, but not all, of the LCLs tested were tumorigenic in SCID mice. Long-term culturing in vitro was not a necessary prerequisite for tumorigenicity. There was a good correlation between in vivo and in vitro growth. Three major classes of cells could be distinguished on the basis of their growth properties.
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Base de dados:
MEDLINE
Assunto principal:
Linfoma Imunoblástico de Células Grandes
/
Linfoma de Burkitt
/
Herpesvirus Humano 4
Idioma:
En
Ano de publicação:
1991
Tipo de documento:
Article