Cullen's sign and massive ovarian enlargement secondary to primary hypothyroidism in a patient with a normal FSH receptor.
Arch Dis Child
; 91(6): 509-10, 2006 Jun.
Article
em En
| MEDLINE
| ID: mdl-16714722
ABSTRACT
Ovarian hyperstimulation is a recognised complication of longstanding hypothyroidism. A 12 year old girl with atrophic thyroiditis who presented with abdominal pain and distension is reported. She was noted to have bruising in the vicinity of the umbilicus (Cullen's sign). She had pronounced ovarian enlargement on ultrasonography and it was hypothesised that this profound phenotype might reflect an abnormal FSH receptor. However sequencing of the FSH receptor was normal. The ovarian enlargement resolved with thyroxine replacement. Physicians and surgeons should consider longstanding hypothyroidism in patients presenting with Cullen's sign.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Puberdade Precoce
/
Receptores do FSH
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Síndrome de Hiperestimulação Ovariana
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Equimose
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Hipotireoidismo
Idioma:
En
Ano de publicação:
2006
Tipo de documento:
Article