Reference values for exhaled nitric oxide (reveno) study.
Respir Res
; 7: 94, 2006 Jun 30.
Article
em En
| MEDLINE
| ID: mdl-16813647
ABSTRACT
BACKGROUND:
Despite the widespread use of fractional exhaled nitric oxide (FENO) as a biomarker of airways inflammation, there are no published papers describing normal FENO values in a large group of healthy adults.OBJECTIVE:
The aim of this study was to establish adult FENO reference values according to the international guidelines.METHODS:
FENO was measured in 204 healthy, non-smoking adults with normal spirometry values using the on-line single-breath technique, and the results were analysed chemiluminescently.RESULTS:
The main result of the study was the significant difference in FENO values between men and women, thus indicating that gender-based reference FENO values are necessary. The FENO levels obtained at expiratory flows of 50 ml/s ranged from 2.6 to 28.8 ppb in men, and from 1.6 to 21.5 ppb in women.CONCLUSION:
We propose reference FENO values for healthy adult men and women that could be used for clinical and research purposes.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Testes Respiratórios
/
Óxido Nítrico
Idioma:
En
Ano de publicação:
2006
Tipo de documento:
Article