MTHFR 677TT genotype increases the risk for cervical artery dissections.
J Neurol Neurosurg Psychiatry
; 77(8): 951-2, 2006 Aug.
Article
em En
| MEDLINE
| ID: mdl-16844951
ABSTRACT
The methylene tetrahydrofolate reductase (MTHFR) C677T polymorphism was studied in 174 German patients with cervical artery dissection (CAD). The results were compared with published data on 927 healthy German controls. In the series of patients, the frequency of T alleles and of TT carriers was slightly higher (13.8%) than among the healthy controls (10.6%). In patients with multiple dissections (n = 50), the proportion of TT carriers (18%) was found to be even higher and correlated with the number of events. The MTHFR C677T polymorphism was suggested to modify the risk for CAD.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Metilenotetra-Hidrofolato Redutase (NADPH2)
/
Dissecção Aórtica
Idioma:
En
Ano de publicação:
2006
Tipo de documento:
Article