A SAS macro for constrained randomization of group-randomized designs.
Comput Methods Programs Biomed
; 83(3): 205-10, 2006 Sep.
Article
em En
| MEDLINE
| ID: mdl-16870302
ABSTRACT
Group-randomized study designs are useful when individually-randomized designs either are not possible, or will not be able to estimate the parameters of interest. Group-randomized trials often have small number of experimental units or groups and strong geographically-induced between-unit correlation, thereby increasing the chance of obtaining a "bad" randomization outcome. It has been suggested to highly constrain the design through restriction to those allocations that meet specified criteria based on certain covariates available at the baseline. We describe a SAS macro that allocates treatment conditions in a two-arm stratified group-randomized design that ensures balance on relevant covariates. The application of the macro is illustrated using two examples of group-randomized designs.
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Base de dados:
MEDLINE
Assunto principal:
Software
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Distribuição Aleatória
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Ensaios Clínicos Controlados Aleatórios como Assunto
Idioma:
En
Ano de publicação:
2006
Tipo de documento:
Article