[Changes in the alpha-macroglobulins during evolution]. / Izmenenie al'fa-makroglobulinov v protsesse évoliutsii.

It has been demonstrated that antigenic properties of alpha-macroglobulins from 6 species of vertebrate and invertebrate animals are rather similar. All proteins consist of identical subunits which are associated by covalent and noncovalent bonds. All of them are presented by glycoproteins and exhibit the capacity to bind proteinases, as well as the capacity to inhibit the latter with respect to protein and low-molecular synthetic substrates.