First Spanish series of intestinal transplantation in adult recipients.
Rev Esp Enferm Dig
; 98(10): 723-39, 2006 Oct.
Article
em En
| MEDLINE
| ID: mdl-17094721
ABSTRACT
BACKGROUND:
short-bowel transplantation has experienced a substantial growth worldwide following improved results from the late 1990's on, and its coverage by Medicare. According to the International Registry (1985-2005), a total of 1,292 intestinal transplants for 1,210 patients in 65 hospitals across 20 countries have been carried out thus far.OBJECTIVE:
to know short-term (6 months) results regarding patient and graft survival from the first Spanish series of intestinal transplants in adult recipients. MATERIAL ANDMETHODS:
we present our experience in the assessment of 20 potential candidates to short-bowel transplantation between June 2004 and October 2005. Of these, 10 patients were rejected and 4 were transplanted, which makes up the sample of our study.RESULTS:
to this date 5 transplants have been carried out in 4 patients (2 retransplants, 2 desmoid tumors, 1 short bowel syndrome after excision as a result of mesenteric ischemia). Upon study completion and after a mean follow-up of 180 days (range 90-190 days) all recipients are alive, and all grafts but one (75%) are fully operational, with complete digestive autonomy. All patients received induction with alemtuzumab except one, who received thymoglobulin; in all induction was initiated with no steroids.CONCLUSIONS:
intestinal transplantation represents a therapeutic option that is applicable in our setting and valid for recipients with an indication who have no other feasible alternative to keep their intestinal failure under control.
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Base de dados:
MEDLINE
Assunto principal:
Enteropatias
/
Intestino Delgado
Idioma:
En
Ano de publicação:
2006
Tipo de documento:
Article