The Amt/MEP/Rh family: structure of AmtB and the mechanism of ammonia gas conduction.
Physiology (Bethesda)
; 21: 419-29, 2006 Dec.
Article
em En
| MEDLINE
| ID: mdl-17119155
ABSTRACT
The atomic structures of the first members of the Amt/MEP/Rh family show that they are 11-crossing membrane proteins that form trimers in the membrane. Each monomer supports a hydrophobic channel that conducts NH(3) but not any water or ions. The reprotonation of NH(3) on the receiving side raises the pH on that side in the absence of metabolism of NH(3), and there is no transfer of protons through the protein.
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Base de dados:
MEDLINE
Assunto principal:
Sistema do Grupo Sanguíneo Rh-Hr
/
Proteínas de Escherichia coli
/
Proteínas de Transporte de Cátions
/
Proteínas de Saccharomyces cerevisiae
/
Amônia
Idioma:
En
Ano de publicação:
2006
Tipo de documento:
Article