Complete remission of multiple myeloma after autoimmune hemolytic anemia: possible association with interferon-alpha.
Am J Hematol
; 82(6): 489-92, 2007 Jun.
Article
em En
| MEDLINE
| ID: mdl-17236186
ABSTRACT
A patient with multiple myeloma (MM) was being maintained on human recombinant interferon-alpha (INF-alpha) after VAD and autologous bone marrow transplantation (pretreated with melphalan). An episode of immune thrombocytopenia and (Coombs positive) autoimmune hemolytic anemia (AIHA) was noted while on maintenance INF-alpha, which remitted when it was withdrawn. Following this event, he achieved a state of stable disease that persists (more than 3 years) with no specific myeloma treatment. This sequence of events suggests a relationship between an immunological reaction induced by INF-alpha and the prolonged phase of stable disease.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Interferon Tipo I
/
Anemia Hemolítica Autoimune
/
Mieloma Múltiplo
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article