Permissive and instructive anterior patterning rely on mRNA localization in the wasp embryo.
Science
; 315(5820): 1841-3, 2007 Mar 30.
Article
em En
| MEDLINE
| ID: mdl-17395827
ABSTRACT
The long-germ mode of embryogenesis, in which segments arise simultaneously along the anteriorposterior axis, has evolved several times in different lineages of the holometabolous, or fully metamorphosing, insects. Drosophila's long-germ fate map is established largely by the activity of the dipteran-specific Bicoid (Bcd) morphogen gradient, which operates both instructively and permissively to accomplish anterior patterning. By contrast, all nondipteran long-germ insects must achieve anterior patterning independently of bcd. We show that bcd's permissive function is mimicked in the wasp by a maternal repression system in which anterior localization of the wasp ortholog of giant represses anterior expression of the trunk gap genes so that head and thorax can properly form.
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Base de dados:
MEDLINE
Assunto principal:
Proteínas Repressoras
/
Vespas
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Regulação da Expressão Gênica no Desenvolvimento
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Proteínas de Insetos
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Padronização Corporal
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RNA Mensageiro Estocado
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Embrião não Mamífero
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article