A comparison of phosphaferrocene and phospharuthenocene ligands in Rh+-catalysed enamide hydrogenation reactions: superior performance of the phospharuthenocene.
Chemistry
; 13(19): 5492-502, 2007.
Article
em En
| MEDLINE
| ID: mdl-17407112
ABSTRACT
Enantiopure Cp*-substituted 3,4-dimethyl-5-phenylphosphametallocene-2-methanols (M=Fe, Ru) have been prepared from the corresponding 2-carboxy-(-)-menthylphospholide anion and elaborated into 2-CH(2)PPh(2) phosphametallocenes (13 M=Fe; 14 M=Ru) and 2-CH(2)PtBuR substituted phospharuthenocenes (R=tBu, Me). The crystal structures of complexes [Rh(1,5-cod)(eta(2)-L)](+)BF(4)(-) (L=13, 14) reveal significantly different aryl group configurations. Comparative studies of the hydrogenation of para-substituted N-acetylcinnamate esters with these pre-catalysts show a superior performance for the phospharuthenocene derivative in terms of both rate and enantioselectivity.
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Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article