Offspring sex ratio and gonadal irradiation in the British Childhood Cancer Survivor Study.
Br J Cancer
; 96(9): 1439-41, 2007 May 07.
Article
em En
| MEDLINE
| ID: mdl-17426701
ABSTRACT
We investigated offspring sex ratio among 6232 offspring born to 3218 survivors of childhood cancer in relation to therapeutic irradiation, and pooled our data with those from two other large-scale studies giving a total of 9685 offspring. Exposure to high-dose gonadal irradiation was not associated with a significant alteration in offspring sex ratio compared to low doses (men P=0.58, women P=0.66). There was also no evidence that the ratio varied with time since cancer diagnosis when comparing survivors treated with radiotherapy vs those without (men P=0.51; women P=0.46). This, the largest study to date, finds no evidence that exposure to radiation affects the offspring sex ratio among survivors of childhood cancer.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Razão de Masculinidade
/
Neoplasias
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article