A high-dose bortezomib neuropathy with sensory ataxia and myelin involvement.
J Neurol Sci
; 263(1-2): 40-3, 2007 Dec 15.
Article
em En
| MEDLINE
| ID: mdl-17612569
ABSTRACT
Bortezomib, a proteasome inhibitor used in the treatment of multiple myeloma, is known to induce an axonal, dose-dependent neuropathy clinically characterized by pain, paresthesias, burning dysesthesias and numbness. In this study, we describe a patient treated with high-dose bortezomib whose main clinical feature was severe sensory ataxia. Electrodiagnostic studies showed, other than axonal changes, myelin involvement.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Inibidores de Proteases
/
Pirazinas
/
Ataxia
/
Ácidos Borônicos
/
Bainha de Mielina
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article