Oxaliplatin-induced immune hemolytic anemia: a case report and review of the literature.
Anticancer Drugs
; 18(8): 973-6, 2007 Sep.
Article
em En
| MEDLINE
| ID: mdl-17667605
ABSTRACT
We report a 59-year-old woman diagnosed with metastasic colorectal cancer who developed immune hemolytic anemia during FOLFOX chemotherapy (oxaliplatin/leucovorin/5-fluorouracil). Immunohematologic studies demonstrated that immune hemolysis was oxaliplatin-mediated. On the basis of this case and in a review of the literature in which 13 cases of previously reported oxaliplatin-induced immune cytopenia have been identified, we suggest some clinical clues regarding the use of oxaliplatin in cancer patients.
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Base de dados:
MEDLINE
Assunto principal:
Compostos Organoplatínicos
/
Anemia Hemolítica Autoimune
/
Antineoplásicos
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article