[Serologic polymorphism of the HLA Class 2 antigens in the Russian population]. / Serologicheskii polimorfizm antigenov HLA klassa 2 v russkoi populiatsii.
Genetika
; 27(9): 1658-61, 1991 Sep.
Article
em Ru
| MEDLINE
| ID: mdl-1778464
ABSTRACT
Two hundred and thirty Russian Moscovities (108 healthy individuals and 122 cadaver kidney donors) were typed for antigens HLA-DR1-DRw10, HLA-DRw52-DRw53, and HLA-DQw1 and DQw3. HLA-DR1, 2, 3, 4, 5 and 7 were investigated in all individuals, the other having been only studied in portions of the material. The HLA class 2 antigens' polymorphism in Russian population has been shown to have features common to all Caucasians. Most widely distributed antigen is DR2 (phenotype frequency is 36%). Antigens DRw8, DR9 and DRw10 are rare. DR allele distribution demonstrated perfect fits to Hardy--Weinberg expectations. Antigens DR5 and DR4 are considered most difficult to define at early stage of the study.
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Base de dados:
MEDLINE
Assunto principal:
Polimorfismo Genético
/
Antígenos de Histocompatibilidade Classe II
Idioma:
Ru
Ano de publicação:
1991
Tipo de documento:
Article