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[Study on the inclusion technology of volatile oil in Shiquandabu pills].
Xu, Hai-xing; Liu, Xiao-ping; Gong, Yun-xia.
Afiliação
  • Xu HX; Department of Pharmaceutical Engineering, School of Chemical Engineering, Wuhan University of Technology, Wuhan 430070, China.
Zhong Yao Cai ; 30(7): 861-2, 2007 Jul.
Article em Zh | MEDLINE | ID: mdl-17944202
ABSTRACT

OBJECTIVE:

To extract volatile oil from Shiquandabu pills and study technological process of its inclusion compound with beta-Cyclodextrin (beta-CD) to improve its stability.

METHODS:

The study was carried out with steam distillation and orthogonal design. The process conditions were studied by determining the utilization and ratio of oil from Shiquandabu pills volatile oil and extract ratio of in-clusion compound. The most important factor was the ratio of oil to beta-CD. and the inclusion compound was identified by FT-IR spectra and XRD.

RESULTS:

The optimum preparation conditions for inclusion were best-established as oil beta-CD was 18, the inclusion time and temperature were for 1.0 hours. at 20 degrees C.

CONCLUSION:

Tne method can be used for increasing volatile oil's stability and its solubility. It is suitable for production of medicinal preparation.
Assuntos
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Base de dados: MEDLINE Assunto principal: Óleos Voláteis / Medicamentos de Ervas Chinesas / Tecnologia Farmacêutica / Beta-Ciclodextrinas Idioma: Zh Ano de publicação: 2007 Tipo de documento: Article
Buscar no Google
Base de dados: MEDLINE Assunto principal: Óleos Voláteis / Medicamentos de Ervas Chinesas / Tecnologia Farmacêutica / Beta-Ciclodextrinas Idioma: Zh Ano de publicação: 2007 Tipo de documento: Article