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Antibacterial thymol derivatives isolated from Centipeda minima.
Liang, Hengxing; Bao, Fukai; Dong, Xiaoping; Tan, Rui; Zhang, Caijun; Lu, Qing; Cheng, Yongxian.
Afiliação
  • Liang H; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, PR China.
Molecules ; 12(8): 1606-13, 2007 Jan 27.
Article em En | MEDLINE | ID: mdl-17960076
Two new monoterpenoids, 8,10-dihydroxy-9(2)-methylbutyryloxythymol (1) and 10-hydroxy-8,9-dioxyisopropylidene-thymol (2), together with five known thymol derivatives: 8,9,10-trihydroxythymol (3), thymol-beta-glucopyranoside (4), 9-hydroxythymol (5), 8,10-dihydroxy-9-isobutyryloxythymol (6), and 8-hydroxy-9,10-diisobutyryloxythymol (7), were isolated from Centipeda minima. Their structures were identified by means of spectroscopic analyses. Interestingly, compound 2 is not an extraction artifact according to a close HPLC examination of material after extraction by analytical MeOH at ambient temperature. The antibacterial activities of compounds 1-7 were evaluated against eight microbial strains by the agar dilution method.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Timol / Asteraceae / Monoterpenos / Antibacterianos Idioma: En Ano de publicação: 2007 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Timol / Asteraceae / Monoterpenos / Antibacterianos Idioma: En Ano de publicação: 2007 Tipo de documento: Article