Differential ionisation of natural antioxidant polyenes in electrospray and nanospray mass spectrometry.
Rapid Commun Mass Spectrom
; 21(23): 3842-8, 2007.
Article
em En
| MEDLINE
| ID: mdl-17979109
ABSTRACT
Carotenoids are natural products with high economic relevance for the pharmaceutical industries and are a common subject for biochemical research. Reported here is a comparative study of the ionisation of carotenoids by electrospray mass spectrometry (ESI-MS) and nanospray mass spectrometry (nanoESI-MS). The results demonstrate that, along with solvent choice, the influence of the different ionisation processes of ESI and nanoESI are fundamental in determining how ionisation is achieved and which ions (molecular ion or protonated molecule) are observed in MS. The increased understanding afforded by this study will help in the development of unequivocal microanalytical methods for carotenoids and related antioxidant polyenes.
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Base de dados:
MEDLINE
Assunto principal:
Polienos
/
Fatores Biológicos
/
Espectrometria de Massas por Ionização por Electrospray
/
Nanotecnologia
/
Microfluídica
/
Antioxidantes
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article