Use of elevated flow rates in preparative subcritical fluid chromatography.
J Chromatogr A
; 1175(1): 112-6, 2007 Dec 14.
Article
em En
| MEDLINE
| ID: mdl-17980372
ABSTRACT
The benefits of using high flow rates in preparative subcritical fluid chromatography are explored. It is demonstrated that chromatograms loaded to onset of peak coalescence do not deteriorate as flow increases. This allows separation of material in very short time periods leading to dramatically increased production rates. A key factor to accessing elevated flows is the use of shorter columns and the resulting decrease in pressure drop.
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Base de dados:
MEDLINE
Assunto principal:
Cromatografia Líquida
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article