Acute renal failure secondary to fenofibrate monotherapy-induced rhabdomyolysis.
Ren Fail
; 29(7): 927-30, 2007.
Article
em En
| MEDLINE
| ID: mdl-17994463
ABSTRACT
Fenofibrate, a fibric acid derivative, is used to treat diabetic dyslipidemia, hypertriglyceridemia, and combined hyperlipidemia alone or in combination with statins. Rhabdomyolysis is defined as a pathological condition of skeletal muscle cell damage leading to the release of toxic intracellular material into the circulation. Its major causes include trauma, ischemia, toxins, metabolic disorders, infections, and drugs. Rhabdomyolysis associated with fenofibrate is extremely rare. In nearly all of the presented cases, there was a predisposing factor for rhabdomyolysis such as diabetes, older age, renal insufficiency, and hypothyroidism. Here, we report a nondiabetic, nonhypothyroidic young female patient without any known prior renal disease presenting with acute renal failure developing after fenofibrate treatment.
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Base de dados:
MEDLINE
Assunto principal:
Fenofibrato
/
Rabdomiólise
/
Injúria Renal Aguda
/
Hipolipemiantes
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article