Determination of the amino acid sequence of cystine-containing peptides by tandem mass spectrometry.
Rapid Commun Mass Spectrom
; 5(4): 156-9, 1991 Apr.
Article
em En
| MEDLINE
| ID: mdl-1804412
ABSTRACT
A method has been developed for the determination of the amino-acid sequence of a cyclic peptide containing cystine. It is based on the reduction of the peptide in a reductive matrix prior to ionization by fast-atom bombardment. The amino-acid sequence of the resulting linear peptide is then determined by tandem mass spectrometry from the spectrum produced by the collision-induced decomposition of the [M + H]+ ion of the peptide.
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Base de dados:
MEDLINE
Assunto principal:
Arginina Vasopressina
/
Lipressina
/
Ocitocina
Idioma:
En
Ano de publicação:
1991
Tipo de documento:
Article