Familial associations with paratuberculosis ELISA results in Texas Longhorn cattle.
Vet Microbiol
; 129(1-2): 131-8, 2008 May 25.
Article
em En
| MEDLINE
| ID: mdl-18055137
ABSTRACT
The objective of this cross-sectional study was to estimate familial associations with paratuberculosis ELISA status in beef cattle. Texas Longhorn cattle (n=715) greater than 2years of age were sampled for paratuberculosis testing using ELISA and fecal culture. Diagnostic test results were indicative of substantial numbers of false-positive serological reactions consistent with environmental exposure to non-MAP Mycobacterium spp. Associations between ancestors and paratuberculosis ELISA status of offspring were assessed using conditional logistic regression. The association between ELISA status of the dam and her offspring was assessed using linear mixed-effect models. Significant associations were identified between some ancestors and offspring ELISA status. The odds of being classified as "suspect" or greater based on ELISA results were 4.6 times greater for offspring of dams with similarly increased SP ratios. A significant positive linear association was also observed between dam and offspring log-transformed SP ratios. Results indicate that there is familial aggregation of paratuberculosis ELISA results in beef cattle and suggest that genetic selection based on paratuberculosis ELISA status may decrease seroprevalence. However, genetic selection may have minimal effect on paratuberculosis control in herds with exposure to non-MAP Mycobacterium spp.
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Base de dados:
MEDLINE
Assunto principal:
Paratuberculose
/
Ensaio de Imunoadsorção Enzimática
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article