Hydrogen and trimethylsilyl transfers during EI mass spectral fragmentation of hydroxycarboxylic and oxocarboxylic acid trimethylsilyl derivatives.
J Am Soc Mass Spectrom
; 19(1): 66-75, 2008 Jan.
Article
em En
| MEDLINE
| ID: mdl-18061477
ABSTRACT
This paper, describing electron ionization mass spectral fragmentation of some hydroxycarboxylic and oxocarboxylic acid trimethylsilyl derivatives, focuses on the formation of fragment ions resulting from the interactions between the two functionalities of these compounds. These interactions result in the formation of fragment ions at [CH2=C(OTMS)2]+., [CH2=CHC(OTMS)=OTMS]+, [M-31]+, [M-105]+, and [M-RCHO]+. in the case of hydroxycarboxylic acid trimethylsilyl derivatives of formula RCHOTMS(CH2)nCOOTMS and at [RC(OTMS)=CH2]+., [RC(=OTMS)CH=CH2]+, and [M-RC(=O)CH2]+ in the case of oxocarboxylic acid trimethylsilyl esters of formula RC(=O)(CH2)nCOOTMS. Some of these fragmentations appeared to be sufficiently specific to be used to characterize these compounds. Several fragmentation pathways involving trimethylsilyl and hydrogen transfers were proposed to explain the formation of these different fragment ions and were substantiated by deuterium labeling.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Compostos de Trimetilsilil
/
Ácidos Carboxílicos
/
Espectrometria de Massas por Ionização por Electrospray
/
Hidrogênio
/
Cromatografia Gasosa-Espectrometria de Massas
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article