Practical, scalable, high-throughput approaches to eta3-pyranyl and eta3-pyridinyl organometallic enantiomeric scaffolds using the Achmatowicz reaction.
J Org Chem
; 73(3): 882-8, 2008 Feb 01.
Article
em En
| MEDLINE
| ID: mdl-18171075
ABSTRACT
A unified strategy for the high-throughput synthesis of multigram quantities of the eta(3)-oxopyranyl- and eta(3)-oxopyridinylmolybdenum complexes TpMo(CO)(2)(eta(3)-oxopyranyl) and TpMo(CO)(2)(eta(3)-oxopyridinyl) is described (Tp = hydridotrispyrazolylborato). The strategy uses the oxa- and aza-Achmatowicz reaction for the preparation of these organometallic enantiomeric scaffolds, in both racemic and high enantiopurity versions.
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Base de dados:
MEDLINE
Assunto principal:
Compostos Organometálicos
/
Piridinas
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article