Research on the distribution of properdin factor B in Sardinia.
Gene Geogr
; 5(1-2): 95-102, 1991.
Article
em En
| MEDLINE
| ID: mdl-1820159
ABSTRACT
This study examines the distribution of properdin factor B by means of electrophoresis on cellulose acetate in a sample of 780 individuals from seven historical/geographical areas of Sardinia Nurra, Goceano, Nuorese, Arborea, Sarcidano, Ogliastra, Campidano di Cagliari. The gene frequencies obtained for the total sample are BF*S = 0.595, BF*F = 0.227, BF*S1 = 0.012, BF*F1 = 0.166. Division of the total sample into subsamples has highlighted some noticeable differences both among the historical/geographical areas considered and with mainland Italy. In Sardinia relatively low frequencies of the allele BF*S are accompanied by exceptionally high incidences of the variant allele BF*F1, which reaches a maximum in the Goceano area (0.2143).
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Base de dados:
MEDLINE
Assunto principal:
Polimorfismo Genético
/
Fator B do Complemento
/
Frequência do Gene
Idioma:
En
Ano de publicação:
1991
Tipo de documento:
Article