[Distribution of tryptophan hydroxylase gene-T457C locus polymorphism in Han ethnic group in northern China].
Fa Yi Xue Za Zhi
; 23(6): 444-5, 2007 Dec.
Article
em Zh
| MEDLINE
| ID: mdl-18402117
ABSTRACT
OBJECTIVE:
To study the distribution of the tryptophan hydroxylase (TPH) gene-T457C locus polymorphism in Han ethnic group in northern China and to find its applicable value in forensic science.METHODS:
Genomic DNA samples, extracted from 180 unrelated individuals in northern Chinese Han population, were analyzed by PCR-RFLP.RESULTS:
The discrimination power (DP) value and the power of exclusion (PE) value of the TPH gene-T457C locus were 0.624 and 0.187, respectively. The allele frequency showed significant difference from that of French people (P=0.04).CONCLUSION:
Polymorphism of the TPH gene-T457C locus could show ethnic and regional differences. It has a potential to be used in forensic science.
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Base de dados:
MEDLINE
Assunto principal:
Polimorfismo Genético
/
Triptofano Hidroxilase
/
Povo Asiático
/
Frequência do Gene
Idioma:
Zh
Ano de publicação:
2007
Tipo de documento:
Article