Functional development of the enteric nervous system--from migration to motility.
Neurogastroenterol Motil
; 20 Suppl 1: 20-31, 2008 May.
Article
em En
| MEDLINE
| ID: mdl-18402639
ABSTRACT
The enteric nervous system (ENS) consists of many different types of enteric neurones forming complex reflex circuits that underlie or regulate many gut functions. Studies of humans with Hirschsprung's disease (distal aganglionosis), and of animal models of Hirschsprung's disease, have led to the identification of many of the genetic, molecular and cellular mechanisms responsible for the colonization of the gut by enteric neurone precursors. However, later events in the ENS development are still poorly understood, including the development of functioning ENS circuits. This article is a personal view of the current state of play in our understanding of the ENS development and of the future of the field.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Movimento Celular
/
Sistema Nervoso Entérico
/
Trato Gastrointestinal
/
Motilidade Gastrointestinal
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article