Expression of genes for thioredoxin 1 and thioredoxin 2 in multidrug resistance ovarian carcinoma cells SKVLB.
Bull Exp Biol Med
; 144(3): 301-3, 2007 Sep.
Article
em En
| MEDLINE
| ID: mdl-18457020
ABSTRACT
The expression of genes for thioredoxin isoforms Trx1 and Trx2 was studied in sensitive SKOV-3 and resistant SKVLB human ovarian carcinoma cells. The development of doxorubicin resistance was accompanied by a significant increase in the expression of TRX1 gene and less pronounced increase in TRX2 gene expression.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias Ovarianas
/
Tiorredoxinas
/
Resistência a Múltiplos Medicamentos
/
Resistencia a Medicamentos Antineoplásicos
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article