A facile access to pyrroles from amino acids via an aza-Wacker cyclization.
J Org Chem
; 73(13): 5180-2, 2008 Jul 04.
Article
em En
| MEDLINE
| ID: mdl-18512990
ABSTRACT
A facile and efficient synthesis of pyrroles from readily available amino acids is described. The key step in the method is an aza-Wacker oxidative cyclization catalyzed by palladium(II)/Cu(OTf)2. A series of pyrroles were obtained by this method under mild conditions.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Pirróis
/
Aminoácidos
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article