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The anti-neurodegeneration drug clioquinol inhibits the aging-associated protein CLK-1.
Wang, Ying; Branicky, Robyn; Stepanyan, Zaruhi; Carroll, Melissa; Guimond, Marie-Pierre; Hihi, Abdelmadjid; Hayes, Steve; McBride, Kevin; Hekimi, Siegfried.
Afiliação
  • Wang Y; Department of Biology, McGill University, Montráal, Quábec H3A 1B1, Canada and Chronogen Inc., Montráal, Quábec H1W 4A4, Canada.
  • Branicky R; Department of Biology, McGill University, Montráal, Quábec H3A 1B1, Canada and Chronogen Inc., Montráal, Quábec H1W 4A4, Canada.
  • Stepanyan Z; Department of Biology, McGill University, Montráal, Quábec H3A 1B1, Canada and Chronogen Inc., Montráal, Quábec H1W 4A4, Canada.
  • Carroll M; Department of Biology, McGill University, Montráal, Quábec H3A 1B1, Canada and Chronogen Inc., Montráal, Quábec H1W 4A4, Canada.
  • Guimond MP; Department of Biology, McGill University, Montráal, Quábec H3A 1B1, Canada and Chronogen Inc., Montráal, Quábec H1W 4A4, Canada.
  • Hihi A; Department of Biology, McGill University, Montráal, Quábec H3A 1B1, Canada and Chronogen Inc., Montráal, Quábec H1W 4A4, Canada.
  • Hayes S; Department of Biology, McGill University, Montráal, Quábec H3A 1B1, Canada and Chronogen Inc., Montráal, Quábec H1W 4A4, Canada.
  • McBride K; Department of Biology, McGill University, Montráal, Quábec H3A 1B1, Canada and Chronogen Inc., Montráal, Quábec H1W 4A4, Canada. Electronic address: kevinmcbride@sympatico.ca.
  • Hekimi S; Department of Biology, McGill University, Montráal, Quábec H3A 1B1, Canada and Chronogen Inc., Montráal, Quábec H1W 4A4, Canada. Electronic address: Siegfried.Hekimi@McGill.Ca.
J Biol Chem ; 284(1): 314-323, 2009 Jan 02.
Article em En | MEDLINE | ID: mdl-18927074
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Envelhecimento / Quelantes / Caenorhabditis elegans / Clioquinol / Proteínas de Caenorhabditis elegans / Proteínas Mitocondriais / Proteínas de Membrana Idioma: En Ano de publicação: 2009 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Envelhecimento / Quelantes / Caenorhabditis elegans / Clioquinol / Proteínas de Caenorhabditis elegans / Proteínas Mitocondriais / Proteínas de Membrana Idioma: En Ano de publicação: 2009 Tipo de documento: Article