Is there a role for second-look capsule endoscopy in patients with obscure GI bleeding after a nondiagnostic first test?
Gastrointest Endosc
; 69(4): 850-6, 2009 Apr.
Article
em En
| MEDLINE
| ID: mdl-18950762
ABSTRACT
BACKGROUND:
Long-term follow-up data on patients with obscure GI bleeding subjected to capsule endoscopy (CE) are missing.OBJECTIVE:
Our purpose was to follow up patients with a nondiagnostic test and determine whether a second-look CE would be beneficial. PATIENTS We enrolled 293 subjects. CE studies were classified as diagnostic (positive findings) or nondiagnostic (findings of uncertain significance/no findings). Patients were followed up for a mean (SD) 24.8 (5.2) months. Outcome was defined as continued or complete resolution of bleeding.INTERVENTIONS:
Patients with a nondiagnostic test were subjected to a repeat CE if they manifested a new bleeding episode or a drop in hemoglobin >or=2 g/dL.RESULTS:
Positive findings, findings of uncertain significance, and no findings were identified in 41.6%, 16.0%, and 42.3% of our patients, respectively. Therapeutic intervention was possible in 72.1% of those with positive findings and in 30% of those with findings of uncertain significance. Complete resolution of bleeding occurred more often in patients with a diagnostic test (65.2%) compared with those with a nondiagnostic test (35.4%, P < .001). Second-look CE was performed in a subgroup of our patients (n = 76) and was diagnostic in those whose presentation changed from occult to overt or those whose hemoglobin dropped >or=4 g/dL.CONCLUSIONS:
In patients with obscure GI bleeding, a diagnostic CE leads to therapeutic interventions and a favorable outcome. Patients with a nondiagnostic test would definitely benefit from a second-look CE if the bleeding presentation changes from occult to overt or if the hemoglobin value drops >or=4 g/dL.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Endoscopia por Cápsula
/
Hemorragia Gastrointestinal
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article