Use of bone marrow mesenchymal (stromal) stem cells in experimental ischemic stroke in rats.
Bull Exp Biol Med
; 145(1): 122-8, 2008 Jan.
Article
em En
| MEDLINE
| ID: mdl-19024019
ABSTRACT
The effects of human mesenchymal stem cells on neurological functions and behavioral reactions of animals and on damaged brain tissue were studied on the model of focal cerebral ischemia in rats. Homing and differentiation of transplanted mesenchymal stem cells were also studied. Significant regression of neurological disorders after cell transplantation was noted, no appreciable shifts were detected by magnetic resonance tomography. Homing of transplanted cells was detected mainly in the zone of focal ischemia. Some cells died, others exhibited signs of differentiation into neurons and glia.
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Base de dados:
MEDLINE
Assunto principal:
Células da Medula Óssea
/
Isquemia Encefálica
/
Acidente Vascular Cerebral
/
Transplante de Células-Tronco Mesenquimais
/
Células-Tronco Mesenquimais
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article