Limonoids of the phragmalin type from Swietenia macrophylla and their chemotaxonomic significance.
J Nat Prod
; 71(12): 1983-7, 2008 Dec.
Article
em En
| MEDLINE
| ID: mdl-19053509
ABSTRACT
Species of Swietenia elaborate limonoid chemistry along only one route, which leads to the mexicanolide type in most species and the phragmalin type in S. mahogani. A hexane extract from leaves of S. macrophylla afforded six new phragmalins with a 8,9,30-ortho-ester unit, namely, 6-O-acetylswietephragmin E (1), 3beta-O-destigloyl-3beta-O-benzoyl-6-O-acetylswietephragmin E (2), 12alpha-acetoxyswietephragmin C (3), 3beta-O-destigloyl-3beta-O-benzoyl-12alpha-acetoxyswietephragmin C (4), 12alpha-acetoxyswietephragmin D (5), and 3beta-O-destigloyl-3beta-O-benzoyl-12alpha-acetoxyswietephragmin D (6). This appears to be the first record of phragamalins from S. macrophylla, and this study shows the potential of tricyclic [3.3.1(2,10).1(1,4)]-decane limonoids as taxonomically useful chemical markers in the Meliaceae.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Meliaceae
/
Limoninas
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article