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Cartilage stress-relaxation proceeds slower at higher compressive strains.
June, Ronald K; Ly, S; Fyhrie, David P.
Afiliação
  • June RK; UCSD, Department of Cellular and Molecular Medicine, La Jolla, CA 92093-0686, USA. rjune@ucsd.edu
Arch Biochem Biophys ; 483(1): 75-80, 2009 Mar 01.
Article em En | MEDLINE | ID: mdl-19111671
ABSTRACT
Articular cartilage is the connective tissue which covers bone surfaces and deforms during in vivo activity. Previous research has investigated flow-dependent cartilage viscoelasticity, but relatively few studies have investigated flow-independent mechanisms. This study investigated polymer dynamics as an explanation for the molecular basis of flow-independent cartilage viscoelasticity. Polymer dynamics predicts that stress-relaxation will proceed more slowly at higher volumetric concentrations of polymer. Stress-relaxation tests were performed on cartilage samples after precompression to different strain levels. Precompression increases the volumetric concentration of cartilage biopolymers, and polymer dynamics predicts an increase in relaxation time constant. Stress-relaxation was slower for greater precompression. There was a significant correlation between the stress-relaxation time constant and cartilage volumetric concentration. Estimates of the flow-dependent timescale suggest that flow-dependent relaxation occurs on a longer timescale than presently observed. These results are consistent with polymer dynamics as a mechanism of cartilage viscoelasticity.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cartilagem Articular Idioma: En Ano de publicação: 2009 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cartilagem Articular Idioma: En Ano de publicação: 2009 Tipo de documento: Article