Detection of human immunodeficiency virus (HIV) type 1 M184V and K103N minority variants in patients with primary HIV infection.
Antimicrob Agents Chemother
; 53(4): 1670-2, 2009 Apr.
Article
em En
| MEDLINE
| ID: mdl-19171798
ABSTRACT
We used an allele-specific real-time PCR assay to explore the presence of K103N and M184V minority species among primary human immunodeficiency virus (HIV) infections and their potential influence in HIV transmission. Thirty randomly chosen antiretroviral drug-naive patients lacking both the K103N and the M184V mutations as determined by conventional sequencing methods were studied, and K103N and M184V viral minority species were found in three (10%) and four (11%) patients, respectively.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Infecções por HIV
/
HIV-1
/
Transcriptase Reversa do HIV
/
Mutação
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article