Adjuvant carboplatin for the treatment of intestinal carcinoid in a dog.
In Vivo
; 22(6): 759-61, 2008.
Article
em En
| MEDLINE
| ID: mdl-19181003
ABSTRACT
A ten-year-old castrated male dog was presented due to a two-day history of constipation and tenesmus. At physical examination, the dog was depressed and unresponsive. Aggressive behavior was elicited by deep abdominal palpation and a mass was detected during the examination. Imaging studies evidenced a large jejunal mass. The lesion (6 cm in diameter) was surgically removed. The histopathology report gave a diagnosis of completely excised intestinal carcinoid. The patient recovered well from the procedure and was scheduled for adjuvant chemotherapy. The dog received four doses of carboplatin (300 mg/m2) every three weeks without showing signs of toxicity. The dog is still in remission after 18 months and is reassessed on a three-month schedule. This report represents the first description of long-term control of intestinal carcinoid in the dog and the first of adjuvant chemotherapy for this rare and aggressive neoplasm.
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Base de dados:
MEDLINE
Assunto principal:
Tumor Carcinoide
/
Carboplatina
/
Doenças do Cão
/
Neoplasias Intestinais
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article